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For the people suffering from Irritable Bowel Syndrome, any course of action that can lessen the severity of symptoms is more than welcomed. There have been studies suggesting that regular intake of probiotics can aid in preventing and lessening the ...

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IBS is often misdiagnosed and many people who don't actually have it believe that they do. On the other hand, many of you who suffer from it might not know it at all. The reason for this is because the symptoms can vary and often be contradictory. An...

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Despite the changing times, people still believe things that are neither true nor accurate about diabetes. Unfortunately, these beliefs can possibly lead to more harm than good to individuals with diabetes and to those who are at risk of developing t...

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There are two major types of diabetes (type 1 and type 2), both of which may be due to either the environment or the person’s genes. At times, because of the fast paced world and the changes in lifestyle and habits, both types of diabetes may be in...

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People who are diagnosed with diabetes manifest varying symptoms of the disease. When their diagnosis is comorbid with other illnesses, the symptoms could become all the more varied, sometimes even to the point of being confusing. But diabetes does h...

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Possible Causes of Type 1 Diabetes. For type 1 diabetes, the definitive causes are not really known. However, experts and researchers claim that there are individuals who are predisposed to developing type 1 diabetes. One of the things that could se...

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The Case of Carol. Sixty-year old Carol has had bouts of knee stiffness for a couple of months. When she wakes up in the morning, she finds it hard to immediately stand up from her resting position because she would experience stiffness on her ankles...

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Osteoarthritis can occur in various parts of the body. Commonly, the disease affects areas that bear people’s weight. However, there are cases wherein they affect locations on the body that do not necessarily bear the brunt of weight. To understand...

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Pain and Osteoarthritis. Although pain is the primary clinical feature of osteoarthritis, the cause if this pain often varies. For instance, there are authorities who claim that the irritation and pain of osteoarthritic patients are exacerbated by pr...

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People who have diabetes often also suffer from other health complications. This article discusses some examples of comorbidities of diabetes and health complications that arise from the condition. Hypertension. Oftentimes people with diabetes al...

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We aim educate everyone about clinical research while making it easier to find nearby trials.

Contact Us

19200 Von Karmen Avenue, Suite 600
Irvine, California, US

Patients Call: (855) 255-7049
Email: patients@trialjoin.com
Whoops! There was an error.
ErrorException (E_WARNING)
file_put_contents(): Only 0 of 184 bytes written, possibly out of free disk space ErrorException thrown with message "file_put_contents(): Only 0 of 184 bytes written, possibly out of free disk space" Stacktrace: #7 ErrorException in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:122 #6 file_put_contents in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:122 #5 Illuminate\Filesystem\Filesystem:put in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Session/FileSessionHandler.php:83 #4 Illuminate\Session\FileSessionHandler:write in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Session/Store.php:128 #3 Illuminate\Session\Store:save in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Session/Middleware/StartSession.php:87 #2 Illuminate\Session\Middleware\StartSession:terminate in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Foundation/Http/Kernel.php:218 #1 Illuminate\Foundation\Http\Kernel:terminateMiddleware in /var/www/trialjoin/vendor/laravel/framework/src/Illuminate/Foundation/Http/Kernel.php:189 #0 Illuminate\Foundation\Http\Kernel:terminate in /var/www/trialjoin/public/index.php:60
7
ErrorException
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Filesystem
/
Filesystem.php
122
6
file_put_contents
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Filesystem
/
Filesystem.php
122
5
Illuminate
\
Filesystem
\
Filesystem
put
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Session
/
FileSessionHandler.php
83
4
Illuminate
\
Session
\
FileSessionHandler
write
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Session
/
Store.php
128
3
Illuminate
\
Session
\
Store
save
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Session
/
Middleware
/
StartSession.php
87
2
Illuminate
\
Session
\
Middleware
\
StartSession
terminate
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Foundation
/
Http
/
Kernel.php
218
1
Illuminate
\
Foundation
\
Http
\
Kernel
terminateMiddleware
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Foundation
/
Http
/
Kernel.php
189
0
Illuminate
\
Foundation
\
Http
\
Kernel
terminate
/
public
/
index.php
60
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Filesystem
/
Filesystem.php
     *
     * @param  string  $path
     * @return string
     */
    public function hash($path)
    {
        return md5_file($path);
    }
 
    /**
     * Write the contents of a file.
     *
     * @param  string  $path
     * @param  string  $contents
     * @param  bool  $lock
     * @return int
     */
    public function put($path, $contents, $lock = false)
    {
        return file_put_contents($path, $contents, $lock ? LOCK_EX : 0);
    }
 
    /**
     * Prepend to a file.
     *
     * @param  string  $path
     * @param  string  $data
     * @return int
     */
    public function prepend($path, $data)
    {
        if ($this->exists($path)) {
            return $this->put($path, $data.$this->get($path));
        }
 
        return $this->put($path, $data);
    }
 
    /**
     * Append to a file.
Arguments
  1. "file_put_contents(): Only 0 of 184 bytes written, possibly out of free disk space"
    
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Filesystem
/
Filesystem.php
     *
     * @param  string  $path
     * @return string
     */
    public function hash($path)
    {
        return md5_file($path);
    }
 
    /**
     * Write the contents of a file.
     *
     * @param  string  $path
     * @param  string  $contents
     * @param  bool  $lock
     * @return int
     */
    public function put($path, $contents, $lock = false)
    {
        return file_put_contents($path, $contents, $lock ? LOCK_EX : 0);
    }
 
    /**
     * Prepend to a file.
     *
     * @param  string  $path
     * @param  string  $data
     * @return int
     */
    public function prepend($path, $data)
    {
        if ($this->exists($path)) {
            return $this->put($path, $data.$this->get($path));
        }
 
        return $this->put($path, $data);
    }
 
    /**
     * Append to a file.
Arguments
  1. "/var/www/trialjoin/storage/framework/sessions/DbioLt6Hsnsc9mY3AbDoyUv7OTO6a7mpOOBZsqL5"
    
  2. "a:3:{s:6:"_token";s:40:"D3uy587xuxyUfQeBkVP3eZrwKnm3HkYthuQJYnZV";s:9:"_previous";a:1:{s:3:"url";s:26:"https://trialjoin.com/blog";}s:6:"_flash";a:2:{s:3:"old";a:0:{}s:3:"new";a:0:{}}}"
    
  3. 2
    
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Session
/
FileSessionHandler.php
    /**
     * {@inheritdoc}
     */
    public function read($sessionId)
    {
        if ($this->files->exists($path = $this->path.'/'.$sessionId)) {
            if (filemtime($path) >= Carbon::now()->subMinutes($this->minutes)->getTimestamp()) {
                return $this->files->get($path, true);
            }
        }
 
        return '';
    }
 
    /**
     * {@inheritdoc}
     */
    public function write($sessionId, $data)
    {
        $this->files->put($this->path.'/'.$sessionId, $data, true);
 
        return true;
    }
 
    /**
     * {@inheritdoc}
     */
    public function destroy($sessionId)
    {
        $this->files->delete($this->path.'/'.$sessionId);
 
        return true;
    }
 
    /**
     * {@inheritdoc}
     */
    public function gc($lifetime)
    {
        $files = Finder::create()
Arguments
  1. "/var/www/trialjoin/storage/framework/sessions/DbioLt6Hsnsc9mY3AbDoyUv7OTO6a7mpOOBZsqL5"
    
  2. "a:3:{s:6:"_token";s:40:"D3uy587xuxyUfQeBkVP3eZrwKnm3HkYthuQJYnZV";s:9:"_previous";a:1:{s:3:"url";s:26:"https://trialjoin.com/blog";}s:6:"_flash";a:2:{s:3:"old";a:0:{}s:3:"new";a:0:{}}}"
    
  3. true
    
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Session
/
Store.php
     *
     * @param  string  $data
     * @return string
     */
    protected function prepareForUnserialize($data)
    {
        return $data;
    }
 
    /**
     * Save the session data to storage.
     *
     * @return bool
     */
    public function save()
    {
        $this->ageFlashData();
 
        $this->handler->write($this->getId(), $this->prepareForStorage(
            serialize($this->attributes)
        ));
 
        $this->started = false;
    }
 
    /**
     * Prepare the serialized session data for storage.
     *
     * @param  string  $data
     * @return string
     */
    protected function prepareForStorage($data)
    {
        return $data;
    }
 
    /**
     * Age the flash data for the session.
     *
     * @return void
Arguments
  1. "DbioLt6Hsnsc9mY3AbDoyUv7OTO6a7mpOOBZsqL5"
    
  2. "a:3:{s:6:"_token";s:40:"D3uy587xuxyUfQeBkVP3eZrwKnm3HkYthuQJYnZV";s:9:"_previous";a:1:{s:3:"url";s:26:"https://trialjoin.com/blog";}s:6:"_flash";a:2:{s:3:"old";a:0:{}s:3:"new";a:0:{}}}"
    
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Session
/
Middleware
/
StartSession.php
        if ($this->sessionConfigured()) {
            $this->storeCurrentUrl($request, $session);
 
            $this->addCookieToResponse($response, $session);
        }
 
        return $response;
    }
 
    /**
     * Perform any final actions for the request lifecycle.
     *
     * @param  \Illuminate\Http\Request  $request
     * @param  \Symfony\Component\HttpFoundation\Response  $response
     * @return void
     */
    public function terminate($request, $response)
    {
        if ($this->sessionHandled && $this->sessionConfigured() && ! $this->usingCookieSessions()) {
            $this->manager->driver()->save();
        }
    }
 
    /**
     * Start the session for the given request.
     *
     * @param  \Illuminate\Http\Request  $request
     * @return \Illuminate\Contracts\Session\Session
     */
    protected function startSession(Request $request)
    {
        return tap($this->getSession($request), function ($session) use ($request) {
            $session->setRequestOnHandler($request);
 
            $session->start();
        });
    }
 
    /**
     * Get the session implementation from the manager.
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Foundation
/
Http
/
Kernel.php
     * @return void
     */
    protected function terminateMiddleware($request, $response)
    {
        $middlewares = $this->app->shouldSkipMiddleware() ? [] : array_merge(
            $this->gatherRouteMiddleware($request),
            $this->middleware
        );
 
        foreach ($middlewares as $middleware) {
            if (! is_string($middleware)) {
                continue;
            }
 
            list($name) = $this->parseMiddleware($middleware);
 
            $instance = $this->app->make($name);
 
            if (method_exists($instance, 'terminate')) {
                $instance->terminate($request, $response);
            }
        }
    }
 
    /**
     * Gather the route middleware for the given request.
     *
     * @param  \Illuminate\Http\Request  $request
     * @return array
     */
    protected function gatherRouteMiddleware($request)
    {
        if ($route = $request->route()) {
            return $this->router->gatherRouteMiddleware($route);
        }
 
        return [];
    }
 
    /**
Arguments
  1. Request {
      #json: null
      #convertedFiles: null
      #userResolver: Closure {
        class: "Illuminate\Auth\AuthServiceProvider"
        this: AuthServiceProvider { …}
        parameters: {
          $guard: {
            default: null
          }
        }
        use: {
          $app: Application { …}
        }
      }
      #routeResolver: Closure {
        class: "Illuminate\Routing\Router"
        this: Router { …}
        use: {
          $route: Route { …}
        }
      }
      +attributes: ParameterBag {}
      +request: ParameterBag {#1}
      +query: ParameterBag {#1}
      +server: ServerBag {}
      +files: FileBag {}
      +cookies: ParameterBag {}
      +headers: HeaderBag {}
      #content: null
      #languages: null
      #charsets: null
      #encodings: null
      #acceptableContentTypes: array:4 [
        0 => "text/html"
        1 => "application/xhtml+xml"
        2 => "application/xml"
        3 => "*/*"
      ]
      #pathInfo: "/blog"
      #requestUri: "/blog"
      #baseUrl: ""
      #basePath: null
      #method: "GET"
      #format: null
      #session: Store {}
      #locale: null
      #defaultLocale: "en"
      -isHostValid: true
      -isForwardedValid: true
      basePath: ""
      format: "html"
    }
    
  2. Response {}
    
/
var
/
www
/
trialjoin
/
vendor
/
laravel
/
framework
/
src
/
Illuminate
/
Foundation
/
Http
/
Kernel.php
     */
    protected function dispatchToRouter()
    {
        return function ($request) {
            $this->app->instance('request', $request);
 
            return $this->router->dispatch($request);
        };
    }
 
    /**
     * Call the terminate method on any terminable middleware.
     *
     * @param  \Illuminate\Http\Request  $request
     * @param  \Illuminate\Http\Response  $response
     * @return void
     */
    public function terminate($request, $response)
    {
        $this->terminateMiddleware($request, $response);
 
        $this->app->terminate();
    }
 
    /**
     * Call the terminate method on any terminable middleware.
     *
     * @param  \Illuminate\Http\Request  $request
     * @param  \Illuminate\Http\Response  $response
     * @return void
     */
    protected function terminateMiddleware($request, $response)
    {
        $middlewares = $this->app->shouldSkipMiddleware() ? [] : array_merge(
            $this->gatherRouteMiddleware($request),
            $this->middleware
        );
 
        foreach ($middlewares as $middleware) {
            if (! is_string($middleware)) {
Arguments
  1. Request {
      #json: null
      #convertedFiles: null
      #userResolver: Closure {
        class: "Illuminate\Auth\AuthServiceProvider"
        this: AuthServiceProvider { …}
        parameters: {
          $guard: {
            default: null
          }
        }
        use: {
          $app: Application { …}
        }
      }
      #routeResolver: Closure {
        class: "Illuminate\Routing\Router"
        this: Router { …}
        use: {
          $route: Route { …}
        }
      }
      +attributes: ParameterBag {}
      +request: ParameterBag {#1}
      +query: ParameterBag {#1}
      +server: ServerBag {}
      +files: FileBag {}
      +cookies: ParameterBag {}
      +headers: HeaderBag {}
      #content: null
      #languages: null
      #charsets: null
      #encodings: null
      #acceptableContentTypes: array:4 [
        0 => "text/html"
        1 => "application/xhtml+xml"
        2 => "application/xml"
        3 => "*/*"
      ]
      #pathInfo: "/blog"
      #requestUri: "/blog"
      #baseUrl: ""
      #basePath: null
      #method: "GET"
      #format: null
      #session: Store {}
      #locale: null
      #defaultLocale: "en"
      -isHostValid: true
      -isForwardedValid: true
      basePath: ""
      format: "html"
    }
    
  2. Response {}
    
/
var
/
www
/
trialjoin
/
public
/
index.php
|--------------------------------------------------------------------------
| Run The Application
|--------------------------------------------------------------------------
|
| Once we have the application, we can handle the incoming request
| through the kernel, and send the associated response back to
| the client's browser allowing them to enjoy the creative
| and wonderful application we have prepared for them.
|
*/
 
$kernel = $app->make(Illuminate\Contracts\Http\Kernel::class);
 
$response = $kernel->handle(
    $request = Illuminate\Http\Request::capture()
);
 
$response->send();
 
$kernel->terminate($request, $response);
 
Arguments
  1. Request {
      #json: null
      #convertedFiles: null
      #userResolver: Closure {
        class: "Illuminate\Auth\AuthServiceProvider"
        this: AuthServiceProvider { …}
        parameters: {
          $guard: {
            default: null
          }
        }
        use: {
          $app: Application { …}
        }
      }
      #routeResolver: Closure {
        class: "Illuminate\Routing\Router"
        this: Router { …}
        use: {
          $route: Route { …}
        }
      }
      +attributes: ParameterBag {}
      +request: ParameterBag {#1}
      +query: ParameterBag {#1}
      +server: ServerBag {}
      +files: FileBag {}
      +cookies: ParameterBag {}
      +headers: HeaderBag {}
      #content: null
      #languages: null
      #charsets: null
      #encodings: null
      #acceptableContentTypes: array:4 [
        0 => "text/html"
        1 => "application/xhtml+xml"
        2 => "application/xml"
        3 => "*/*"
      ]
      #pathInfo: "/blog"
      #requestUri: "/blog"
      #baseUrl: ""
      #basePath: null
      #method: "GET"
      #format: null
      #session: Store {}
      #locale: null
      #defaultLocale: "en"
      -isHostValid: true
      -isForwardedValid: true
      basePath: ""
      format: "html"
    }
    
  2. Response {}
    

Environment & details:

empty
empty
empty
empty
empty
Key Value
REDIRECT_HTTPS
"on"
REDIRECT_SSL_TLS_SNI
"trialjoin.com"
REDIRECT_STATUS
"200"
HTTPS
"on"
SSL_TLS_SNI
"trialjoin.com"
SSL_SERVER_S_DN_CN
"*.trialjoin.com"
SSL_SERVER_I_DN_C
"US"
SSL_SERVER_I_DN_O
"DigiCert Inc"
SSL_SERVER_I_DN_OU
"www.digicert.com"
SSL_SERVER_I_DN_CN
"GeoTrust TLS RSA CA G1"
SSL_SERVER_SAN_DNS_0
"*.trialjoin.com"
SSL_SERVER_SAN_DNS_1
"trialjoin.com"
SSL_VERSION_INTERFACE
"mod_ssl/2.4.18"
SSL_VERSION_LIBRARY
"OpenSSL/1.0.2g"
SSL_PROTOCOL
"TLSv1.2"
SSL_SECURE_RENEG
"true"
SSL_COMPRESS_METHOD
"NULL"
SSL_CIPHER
"ECDHE-RSA-AES256-SHA"
SSL_CIPHER_EXPORT
"false"
SSL_CIPHER_USEKEYSIZE
"256"
SSL_CIPHER_ALGKEYSIZE
"256"
SSL_CLIENT_VERIFY
"NONE"
SSL_SERVER_M_VERSION
"3"
SSL_SERVER_M_SERIAL
"0483C36ACDF14162FEFD91BE08CDD241"
SSL_SERVER_V_START
"Dec 28 00:00:00 2017 GMT"
SSL_SERVER_V_END
"Jan 27 12:00:00 2019 GMT"
SSL_SERVER_S_DN
"CN=*.trialjoin.com"
SSL_SERVER_I_DN
"CN=GeoTrust TLS RSA CA G1,OU=www.digicert.com,O=DigiCert Inc,C=US"
SSL_SERVER_A_KEY
"rsaEncryption"
SSL_SERVER_A_SIG
"sha256WithRSAEncryption"
SSL_SESSION_ID
"f4bb69d44d2ad4aba608c0a5f58f26e31c76eb9320bb4e0511d6154c40a2f963"
SSL_SESSION_RESUMED
"Initial"
HTTP_USER_AGENT
"CCBot/2.0 (https://commoncrawl.org/faq/)"
HTTP_ACCEPT
"text/html,application/xhtml+xml,application/xml;q=0.9,*/*;q=0.8"
HTTP_IF_MODIFIED_SINCE
"Fri, 19 Oct 2018 22:07:15 GMT"
HTTP_HOST
"trialjoin.com"
HTTP_CONNECTION
"Keep-Alive"
HTTP_ACCEPT_ENCODING
"gzip"
PATH
"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/sbin:/bin"
SERVER_SIGNATURE
"<address>Apache/2.4.18 (Ubuntu) Server at trialjoin.com Port 443</address>\n"
SERVER_SOFTWARE
"Apache/2.4.18 (Ubuntu)"
SERVER_NAME
"trialjoin.com"
SERVER_ADDR
"192.241.173.169"
SERVER_PORT
"443"
REMOTE_ADDR
"54.167.15.6"
DOCUMENT_ROOT
"/var/www/trialjoin/public"
REQUEST_SCHEME
"https"
CONTEXT_PREFIX
""
CONTEXT_DOCUMENT_ROOT
"/var/www/trialjoin/public"
SERVER_ADMIN
"webmaster@localhost"
SCRIPT_FILENAME
"/var/www/trialjoin/public/index.php"
REMOTE_PORT
"50432"
REDIRECT_URL
"/blog"
GATEWAY_INTERFACE
"CGI/1.1"
SERVER_PROTOCOL
"HTTP/1.1"
REQUEST_METHOD
"GET"
QUERY_STRING
""
REQUEST_URI
"/blog"
SCRIPT_NAME
"/index.php"
PHP_SELF
"/index.php"
REQUEST_TIME_FLOAT
1544705744.091
REQUEST_TIME
1544705744
APP_NAME
"Laravel"
APP_ENV
"local"
APP_KEY
"base64:Y6eAJzTDbYfZK6VMvJM4WneK1MJXADTUWotu9WAGd94="
APP_DEBUG
"true"
APP_LOG_LEVEL
"debug"
APP_URL
"http://localhost"
BROADCAST_DRIVER
"log"
CACHE_DRIVER
"file"
SESSION_DRIVER
"file"
QUEUE_DRIVER
"sync"
REDIS_HOST
"127.0.0.1"
REDIS_PASSWORD
"null"
REDIS_PORT
"6379"
MAIL_DRIVER
"smtp"
MAIL_HOST
"smtp.mailtrap.io"
MAIL_PORT
"2525"
MAIL_USERNAME
"null"
MAIL_PASSWORD
"null"
MAIL_ENCRYPTION
"null"
PUSHER_APP_ID
""
PUSHER_APP_KEY
""
PUSHER_APP_SECRET
""
Key Value
APP_NAME
"Laravel"
APP_ENV
"local"
APP_KEY
"base64:Y6eAJzTDbYfZK6VMvJM4WneK1MJXADTUWotu9WAGd94="
APP_DEBUG
"true"
APP_LOG_LEVEL
"debug"
APP_URL
"http://localhost"
BROADCAST_DRIVER
"log"
CACHE_DRIVER
"file"
SESSION_DRIVER
"file"
QUEUE_DRIVER
"sync"
REDIS_HOST
"127.0.0.1"
REDIS_PASSWORD
"null"
REDIS_PORT
"6379"
MAIL_DRIVER
"smtp"
MAIL_HOST
"smtp.mailtrap.io"
MAIL_PORT
"2525"
MAIL_USERNAME
"null"
MAIL_PASSWORD
"null"
MAIL_ENCRYPTION
"null"
PUSHER_APP_ID
""
PUSHER_APP_KEY
""
PUSHER_APP_SECRET
""
0. Whoops\Handler\PrettyPageHandler